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Preparation and characterization of antioxidant flavonoid-enriched extract from saffron by-product: a combination of ultrasound-assisted extraction and macroporous resin purification

Abstract The stigma of saffron, a precious spice widely used in the world, takes only 7.4% (w/w) of the total weight of the flower, resulting in wasting the rest 92.6% of the flower. The utilization of the waste saffron floral bio-residues (SFB) has hence attracted people’s attention. In this paper, ultrasound-assisted extraction (UAE) associated with […]

Preparation and characterization of antioxidant flavonoid-enriched extract from saffron by-product: a combination of ultrasound-assisted extraction and macroporous resin purification Read More »

Transcriptomic analysis of saffron at different flowering stages using RNA sequencing uncovers cytochrome P450 genes involved in crocin biosynthesis

Abstract Saffron is a well-known Chinese traditional herb, and crocin biosynthesis is related to the yield and quality of saffron. This study aimed to screen differentially expressed genes (DEGs) in saffron at different flowering stages and identify cytochrome P450 (CYP) genes involved in crocin biosynthesis. Saffron samples at different flowering stages were used for RNA

Transcriptomic analysis of saffron at different flowering stages using RNA sequencing uncovers cytochrome P450 genes involved in crocin biosynthesis Read More »

Effective and simple approach for colchicine determination in saffron parts

OlhaMykhailenkoaLiudasIvanauskasbIvanBezrukaMindaugasMarksabOlgaBorodinacVictoriyaGeorgiyantsa aPharmaceutical Chemistry Department, National University of Pharmacy of the Ministry of Health of Ukraine, 4-Valentinivska st., 61168 Kharkiv, Ukraine bAnalytical and Toxicological Chemistry Department, Lithuanian University of Health Sciences, A. Mickevičiaus g. 9, LT 44307 Kaunas, Lithuania cMedical Biology Department, Kharkiv National Medical University, 4 Nauky Ave, 61022 Kharkiv, Ukraine Received 12 March 2021,

Effective and simple approach for colchicine determination in saffron parts Read More »

Pulsed electric fields (PEF) as hot air drying pre-treatment: Effect on quality and functional properties of saffron (Crocus sativus L.)

LiliaNeriaMariannaGiancaterinoaRacheleRocchiaUrszulaTylewiczbcLucaValbonettiaMarcoFaietaaPaolaPittiaa aFaculty of Bioscience and Technologies for Food, Agriculture, and Environment, University of Teramo, Via Renato Balzarini 1, 64100 Teramo, Italy bDepartment of Agricultural and Food Sciences, University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy cInterdepartmental Centre for Agri-Food Industrial Research, University of Bologna, Via Quinto Bucci 336, 47521 Cesena, Italy Received 20 August

Pulsed electric fields (PEF) as hot air drying pre-treatment: Effect on quality and functional properties of saffron (Crocus sativus L.) Read More »

Quality determination of Crocus sativus L. flower by high-performance liquid chromatography

NataliaMoratalla-LópezaAna M.SánchezbCándidaLorenzoaHoracioLópez-CórcolescGonzalo L.AlonsoaaCátedra de Química Agrícola, ETSI Agrónomos y Montes, Universidad de Castilla-La Mancha, Campus Universitario, 02071, Albacete, SpainbUnidad de Hortofruticultura, Centro de Investigación y Tecnología Agroalimentaria de Aragón, CITA. Instituto Agroalimentario de Aragón IA2 (CITA-Universidad de Zaragoza), Avda. Montañana 930, 50059, Zaragoza, SpaincInstituto Técnico Agronómico Provincial (ITAP), S.A. Avda. Gregorio Arcos, s/n., Albacete, 02006,

Quality determination of Crocus sativus L. flower by high-performance liquid chromatography Read More »

Valorization of Algerian Saffron: Stigmas and Flowers as Source of Bioactive Compounds

Larbi Belyagoubi,  Bouchra Loukidi,  Nabila Belyagoubi-Benhammou,  Angelo Gismondi,  Gabriele Di Marco,  Alessia D’Agostino,  Antonella Canini,  Assia Benmahieddine,  Karima Rouigueb,  Dounia Ben Menni &  Fawzia Atik-Bekkara  Abstract Purpose Saffron is widely used for its medicinal and culinary properties. Its stigmas are the most expensive part comparing with the flowers that are discarded during production. For that, the

Valorization of Algerian Saffron: Stigmas and Flowers as Source of Bioactive Compounds Read More »

Crocus-derived compounds alter the aggregation pathway of Alzheimer’s Disease – associated beta amyloid protein

Nikolaos Stavros Koulakiotis,  Pasi Purhonen,  Evangelos Gikas,  Hans Hebert &  Anthony Tsarbopoulos  Scientific Reports volume 10, Article number: 18150 (2020)  A Publisher Correction to this article was published on 02 February 2021 Abstract Natural products have played a dominant role in the discovery of lead compounds for the development of drugs aimed at the treatment of human diseases. This electrospray ionization-ion mobility spectrometry-mass

Crocus-derived compounds alter the aggregation pathway of Alzheimer’s Disease – associated beta amyloid protein Read More »

Effects of Ultrasound-Assisted and Direct Solvent Extraction Methods on the Antioxidant and Antibacterial Properties of Saffron (Crocus sativus L.) Corm Extract

Mozhgan Esmaeelian,  Moslem Jahani,  Javad Feizy &  Soodabeh Einafshar  Food Analytical Methods volume 14, pages74–87 (2021)Cite this article Abstract In this study, the response surface methodology (RSM) based on a central composite face-centered design (CCD) was used to optimize the extraction of bioactive constituents from Crocus sativus corms. The ultrasound-assisted extraction (UAE) was compared with the conventional direct solvent extraction (DSE)

Effects of Ultrasound-Assisted and Direct Solvent Extraction Methods on the Antioxidant and Antibacterial Properties of Saffron (Crocus sativus L.) Corm Extract Read More »

Pullulan films loading saffron extract encapsulated in nanoliposomes; preparation and characterization.

International Journal Of Biological MacromoleculesZahra Najafi, C J F Kahn, Fatih Bildik, Elmira Arab-Tehrany, Neşe Şahin-Yeşilçubuk Abstract Nanoencapsulation of saffron extract (SE) components into the rapeseed lecithin nanoliposomes were performed by sonication of their aqueous dispersions as a green process. Dynamic light scattering (DLS) results exhibited that empty and SE loaded nanoliposomes (SENL) had average sizes in range of

Pullulan films loading saffron extract encapsulated in nanoliposomes; preparation and characterization. Read More »

Nanoliposomal encapsulation of saffron bioactive compounds; characterization and optimization

Roxana Hadavi 1, Seid Mahdi Jafari 2, Iman Katouzian 1 Affiliations 1Department of Food Materials and Process Design Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran. 2Department of Food Materials and Process Design Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran. Electronic address: smjafari@gau.ac.ir. PMID: 32910968 DOI: 10.1016/j.ijbiomac.2020.09.028 Abstract Nanoliposomes are among the most important lipid-based

Nanoliposomal encapsulation of saffron bioactive compounds; characterization and optimization Read More »


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